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| Name | ginsenoside Rb1 |
| Common Name | ginsenoside Rb1 |
| Chemical Formula | C54H92O23 |
| Chemical Class | triterpene saponin |
| IUPAC Name | (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-3-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-12-hydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]oxy]-6-[[(2R,3S,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-3,5-dihydroxyoxan-4-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol |
| CAS Number | 41753-43-9 |
| Molecular Weight | 1109.2900 g/mol |
| Therapeutic Action | Allopathic:Anti-inflammatory; Allopathic:Antioxidant; Allopathic:neuroprotective; Herbal:adaptogen; TCM:tonifies qi and yin; Ayurvedic:rejuvenative |
| Toxicity | low toxicity; LD50 > 5000 mg/kg oral in rodents |
| Solubility | soluble in water; methanol; ethanol |
| Pharmacological Effects | inhibits NF-kappaB; protects against beta-amyloid induced neurotoxicity; improves cognitive function; anti-fatigue; immunomodulator |
| Found in Herbs | Panax ginseng; Panax japonicus; Panax notoginseng; Panax quinquefolius |
| Found in Foods | |
| Found in Drugs |
| Research Notes | Major protopanaxadiol-type ginsenoside; metabolized to compound K by gut microbiota; shown to cross blood-brain barrier in animal models; potential for neurodegenerative diseases |
| Reference | PubChem CID 9894555 |
| URL | https://pubchem.ncbi.nlm.nih.gov/compound/9894555 |
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