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| Name | ginsenoside Rg1 |
| Common Name | ginsenoside Rg1 |
| Chemical Formula | C42H72O14 |
| Chemical Class | triterpene saponin; ginsenoside; dammarane-type tetracyclic triterpenoid saponin |
| IUPAC Name | 2-[2-[[2-[(2S,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-4,4,8,10,14-pentamethyl-17-[(2R)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol |
| CAS Number | 22427-39-0 |
| Molecular Weight | 801.0100 g/mol |
| Therapeutic Action | Allopathic: nootropic; neuroprotective; Anti-inflammatory; Antioxidant; immunomodulator; Herbal: adaptogen; TCM: tonifies qi and yin; generates fluids; calms spirit |
| Toxicity | low acute toxicity; LD50 >5000 mg/kg oral in rodents; generally well tolerated |
| Solubility | soluble in water; soluble in methanol; soluble in ethanol |
| Pharmacological Effects | enhances cognitive function; promotes neurogenesis; modulates NF-kB pathway; increases BDNF expression; improves memory and learning; anti-fatigue; Cardioprotective; anti-apoptotic in neuronal cells |
| Found in Herbs | Panax ginseng; Panax notoginseng; Panax quinquefolius; Panax japonicus; Panax wangianus; Panax zingiberensis; Panax stipuleanatus |
| Found in Foods | |
| Found in Drugs |
| Research Notes | studied for neuroprotection in Alzheimer's models; enhances hippocampal neurogenesis; modulates immune response; potential for cognitive enhancement and recovery from nervous exhaustion |
| Reference | PubChem CID 441923 |
| URL | https://pubchem.ncbi.nlm.nih.gov/compound/441923 |
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